| Camptothecin (NSC-100880) | Camptothecin (NSC-100880, CPT, Campathecin, (S)-(+)-Camptothecin) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM in a cell-free assay. Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways. Phase 2. | 348.35 | 7689-03-4 |
| Ellagic acid | Ellagic acid (Elagostasine, Gallogen) has antiproliferative and antioxidant property. | 302.19 | 476-66-4 |
| Cefoselis Sulfate | Cefoselis (FK 037 Sulfate) is a widely used beta-lactam antibiotic. | 620.64 | 122841-12-7 |
| Sulfapyridine | Sulfapyridine is a sulfonamide antibacterial. | 249.29 | 144-83-2 |
| Paliperidone | Paliperidone, the main active metabolite of Risperidone, is a potent serotonin-2A and dopamine-2 receptor antagonist, used in the treatment of schizophrenia. | 426.48 | 144598-75-4 |
| Lornoxicam | Lornoxicam (Chlortenoxicam) is a non-steroidal COX-1/COX-2 inhibitor, used as an anti-inflammatory drug to treat pain, osteoarthritis, and rheumatoid arthritis. | 371.82 | 70374-39-9 |
| Vinpocetine | Vinpocetine (RGH-4405,Ethyl apovincaminate,AY 27255) is a selective inhibitor of voltage-sensitive sodium channel for the treatment of stroke, vascular dementia and Alzheimer's disease. | 350.45 | 42971-09-5 |
| (-)-Huperzine A (HupA) | (-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonist. Phase 4. | 242.32 | 102518-79-6 |
| Diosmin | Diosmin is an agonist of the aryl hydrocarbon receptor (AhR). Diosmin is a semisynthetic phlebotropic agent and a flavonoid found in a variety of citrus fruits. | 608.55 | 520-27-4 |
| Rheochrysidin | Rheochrysidin (Physcione) is an anthraquinone from roots of Rheum officinale Baill. | 284.26 | 521-61-9 |
| Hypoxanthine | Hypoxanthine, a naturally occurring purine derivative, an intermediate product of uric acid synthesis, formed from adenylic acid and itself a precursor of xanthine. | 136.11 | 68-94-0 |
| Itraconazole (R 51211) | Itraconazole (R 51211) is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy. | 705.65 | 84625-61-6 |
| 7-Aminocephalosporanic acid | 7-Aminocephalosporanic acid is used for synthesis of cephalosporin antibiotics and intermediates. | 272.28 | 957-68-6 |
| Droxidopa | Droxidopa (L-DOPS) is a psychoactive drug and acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). | 213.19 | 23651-95-8 |
| Lupeol | Lupeol (Clerodol, Monogynol B, Fagarasterol, Farganasterol) is a significant lupane-type triterpene represented in the plant, fungi and animal kingdoms with anticancer, antiprotozoal, chemopreventive and anti-inflammatory properties. | 426.72 | 545-47-1 |
| Cefadroxil hydrate | Cefadroxil(BL-S 578 hydrate) is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections. | 381.40 | 66592-87-8 |
| Sodium Aescinate | Sodium Aescinate (SA, Escin Sodium Salt) is a widely-applied triterpene saponin product derived from horse chestnut seeds, possessing vasoactive and organ-protective activities with oral or injection administration in the clinic. Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities. Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway. | 1123.21 | 20977-05-3 |
| Sodium Houttuyfonate | Sodium Houttuyfonate, the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis. | 330.42 | 1847-58-1 |
| Nuciferine | Nuciferine (Sanjoinine E, (-)-Nuciferine, VLT 049) is a major active aporphine alkaloid from the leaves of N. nucifera Gaertn and possesses anti-hyperlipidemia, anti-hypotensive, anti-arrhythmic, and insulin secretagogue activities. Nuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 μM), an inverse agonist at 5-HT7 (IC50=150 nM), a partial agonist at D2 (EC50=64 nM), D5 (EC50=2.6 μM) and 5-HT6 (EC50=700 nM), an agonist at 5-HT1A (EC50=3.2 μM) and D4 (EC50=2 μM) receptor. | 295.38 | 475-83-2 |
| Vincamine | Vincamine (Angiopac, Devincan, Equipur, Minorin, Novicet, Oxybral, Perval, Sostenil, Tripervan), an indole alkaloid found in the leaves of V. minor and C. roseus, is a peripheral vasodilator that increases blood flow to the brain. | 354.44 | 1617-90-9 |
| Sennoside A | Sennoside A (NSC 112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine. | 862.74 | 81-27-6 |
| Retinyl (Vitamin A) Palmitate | Retinyl (Vitamin A) Palmitate is a more stable, synthetic version of the essential nutrient vitamin A joined to palmitic acid. | 524.86 | 79-81-2 |
| Chlortetracycline HCl (NSC 13252) | Chlortetracycline HCl (NSC 13252, 7-Chlorotetracycline, Aureomycin monohydrochloride) is the first identified tetracycline antibiotic. | 515.34 | 64-72-2 |
| Folic acid | Folic acid (Folacin, Vitamin B9, Vitamin M, Pteroylglutamic acid, Folate), a B vitamin, plays an important role in cell division and in the synthesis of amino acids and nucleic acids like DNA. | 441.40 | 59-30-3 |
| 6-Aminopenicillanic acid | 6-Aminopenicillanic acid (6-APA) is the central component of penicillin β-lactam antibiotics which are generated by Penicillium. It is used as precursor for antibiotic compounds ampicillin and amoxicillin. | 216.26 | 551-16-6 |
| Bilibubin | Bilibubin (Bilirubin) is a tetrapyrrole and a breakdown product of heme catabolism that acts as a physiological, chain-breaking antioxidant. | 584.66 | 635-65-4 |
| Dihydrocholesterol | Dihydrocholesterol (Beta-Cholestanol, Zymostanol, 5alpha-Cholestanol) is a cholesterol derivative found in human feces, gallstones, eggs, and other biological matter. | 388.67 | 80-97-7 |
| Coumarin 6 | Coumarin 6 is a fluorescent dye frequently used to facilitate the traceability of drug delivery systems in vitro. | 350.43 | 38215-36-0 |
| Coptisine chloride | Coptisine (Q-100696, NSC-119754) is an isoquinoline alkaloid isolated from Coptidis Rhizoma with anti-diabetic, antimicrobial, antiviral, anti-hepatoma, and anti-leukemia effects. Coptisine chloride is an efficient uncompetitive IDO inhibitor with IC50 value of 6.3 μM and Ki value of 5.8 μM. | 355.77 | 6020-18-4 |
| Ellagic Acid hydrate | Ellagic acid is a potent inhibitor of protein kinase CK2 with IC50s of 0.04, 2.9 and 3.5 μM for CK2, Lyn and PKA respectively. It shows potent antioxidant, anti-mutagenic and antidepressant properties. | 320.21 | 314041-08-2 |
| 6-Biopterin | 6-Biopterin ( L-Biopterin, L-Erythro-Biopterin) is a natural product that has been considered as a growth factor for some insects. | 237.22 | 22150-76-1 |
| Xanthopterin Hydrate | Xanthopterin, isolated from butterfly wings and found in many other sources, replace folic acid in the nutrition of many animal species. | 197.15 | 5979-01-1 |
| Indoximod (NLG-8189) | Indoximod (NLG-8189, 1-Methyl-D-tryptophan, 1-MT), a methylated tryptophan, acts as an IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor, and reverses IDO-mediated immune suppression. Phase 2.This product has poor solubility, animal experiments are available, cell experiments please choose carefully! | 218.25 | 110117-83-4 |
| Hederacoside D | Hederacoside D is one of the major bioactive saponins and plays pivotal roles in the overall biological activity. | 1075.24 | 760961-03-3 |
| Dipsacoside B | Dipsacoside B, extracted from the flowerbuds of Lonicera confusa DC, shows strong antimicrobial activity. | 1075.24 | 33289-85-9 |
| Pseudoprotodioscin | Pseudoprotodioscin is a steroidal saponin from plants and exhibits anti-inflammatory and anticancer activities. Pseudoprotodioscin inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides. | 1031.18 | 102115-79-7 |
| Ginsenoside Rb2 | Ginsenoside Rb2 (Ginsenoside C) is a ginsenoside found in Panax ginseng that has a role as a plant metabolite, an antiviral agent and a hypoglycemic agent. | 1079.27 | 11021-13-9 |
| Anemoside B4 | Anemoside B4 (Pulchinenoside B4, Chinensioside A, Pulchinenoside C, Pulsatilla saponin B4), extracted from the herb of Pulsatilla chinensis (Bge.) Regel, is a potential antiviral constituent and inhibits the secretion of IL-10. | 1221.38 | 129741-57-7 |
| Tritetradecanoin | Tritetradecanoin, found in Myristica fragrans Houtt., is used as an antiadhesion agent and lubricating agent. | 723.16 | 555-45-3 |
| Tiliroside | Tiliroside, a glycosidic flavonoid, possesses anti-inflammatory, antioxidant, anticarcinogenic and hepatoprotective activities. | 594.52 | 20316-62-5 |
| Acetylshikonin | Acetylshikonin is a biologically active compound with anti-cancer and anti-inflammatory activity, which is isolated from the roots of Lithospermum erythrorhizoma. It is a novel general P450 inhibitor with IC50 values of 1.4-4.0 μM for all tested P450s. | 330.33 | 24502-78-1 |
| Uvaol | Uvaol is a pentacyclic triterpene, found in the non-glyceride fraction of olive pomace oil, exhibiting both pro- and anti-inflammatory properties. | 442.72 | 545-46-0 |
| Sulfaquinoxaline sodium | Sulfaquinoxaline sodium (N'1-quinoxalin-2-ylsulphanilamide sodium, SQ-Na) is the sodium salt of sulfaquinoxaline, which is often used as a drug to prevent coccidiosis in poultry, swine, and sheep by inhibiting the synthesis of nucleic acids and proteins in microorganisms. | 322.32 | 967-80-6 |
| Cephalexin | Cephalexin (Cefalexin) is an antibiotic that can treat a number of bacterial infections. | 347.39 | 15686-71-2 |
| Tomatidine Hydrochloride | Tomatidine Hydrochloride, a natural steroidal alkaloid, possesses potent antibacterial activity and has anti-inflammatory effects in macrophages. | 452.11 | 6192-62-7 |
| 5a-Pregnane-3,20-dione | 5a-Pregnane-3,20-dione (5alphaP, 5-a-dihydroprogesterone, 3,20-allopregnanedione, 5-Alpha-Dihydro Progesterone) is the endogenous progesterone metabolite. 5a-Pregnane-3,20-dione depolymerizes actin and decreases expression of actin and vinculin. 5a-Pregnane-3,20-dione is involved in promoting breast neoplasia and metastasis by affecting adhesion and cytoskeletal molecules. | 316.48 | 566-65-4 |
| Demethyleneberberine | Demethyleneberberine (DMB), a component of Cortex Phellodendri Chinensis (CPC), significantly alleviates the weight loss and diminishes myeloperoxidase (MPO) activity, while significantly reduces the production of pro-inflammatory cytokines, such as interleukin (IL)-6 and tumor necrosis factor-α (TNF-α), and inhibits the activation of NF-κB signaling pathway. Demethyleneberberine (DMB) potentially ameliorates NAFLD (Non-alcoholic fatty liver disease) by activating AMPK pathways. | 324.35 | 25459-91-0 |
| Stylopine | Stylopine ((R,S)-Stylopine, Tetrahydrocoptisine) reduces nitric oxide (NO), prostaglandin E2 (PGE2), tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta), and the IL-6 production and cyclooxygenase-2 (COX-2) activity caused by the LPS stimulation. Stylopine is a major component of the leaf of Chelidonium majus L. | 323.34 | 4312-32-7 |
| 3-Nitro-L-tyrosine | 3-Nitro-L-tyrosine (3-NT, N-Tyr, MNT), synthesized from L-tyrosine by peroxynitrite, is a product of nitric oxide and superoxide. 3-Nitro-L-tyrosine inhibits the hemodynamic responses to angiotensin II, possibly through the inhibition of alpha 1-adrenoceptor-mediated events. | 226.19 | 621-44-3 |
| Pectolinarin | Pectolinarin is a major compound in Cirsium setidens with anti-inflammatory activity. Pectolinarin inhibits secretion of IL-6 and IL-8, as well as the production of PGE2 and NO. Pectolinarin induces apoptosis via inactivation of the PI3K/Akt pathway. | 622.57 | 28978-02-1 |
| Chelerythrine | Chelerythrine (Toddaline, Broussonpapyrine) is a potent, selective antagonist of PKC with an IC50 of 0.66 μM. Chelerythrine also inhibits the BclXL-Bak BH3 peptide binding with an IC50 of 1.5 μM. Chelerythrine shows antitumor, antidiabetic and anti-inflammatory activity. | 348.37 | 34316-15-9 |
| Spinosad | Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete, is a biological neurotoxic insecticide with a broader action spectrum, targeting the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system. | 731.96 | 168316-95-8 |
| Pseudocoptisine chloride | Pseudocoptisine chloride (Isocoptisine chloride) is a quaternary alkaloid with benzylisoquinoline skeleton isolated from Corydalis Tuber, inhibits acetylcholinesterase (AChE) activity with an IC50 of 12.8 μM, showing anti-inflammatory and anti-amnestic effects. | 355.77 | 30044-78-1 |
| Solasodine | Solasodine (Purapuridine, Solancarpidine, Solasodin, Salasodine, Salasdine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine reduces the mRNA level of matrix metalloproteinase-2 (MMP-2), MMP-9 and extracellular inducer of matrix metalloproteinase (EMMPRIN), but increases the expression of reversion-inducing cysteine-rich protein with kazal motifs (RECK). Solasodine downregulates oncogenic microRNA-21 (miR-21), which has been known to target RECK. Solasodine also reduces PI3K/Akt signaling pathways and downregulates expression of miR-21. | 413.64 | 126-17-0 |
| Cholestenone | 4-Cholesten-3-one is an intestinal metabolite of Cholesterol. It shows an anti-obesity effect on animals. | 384.64 | 601-57-0 |
| 1-Nonadecanol | 1-Nonadecanol is a saturated fatty alcohol. 1-Nonadecanol is one of the compositions of supercritical carbon dioxide (SC-CO2) essential oil of Heracleum thomsonii. 1-Nonadecanol is also an important aroma compound in Neotinea ustulata. | 284.52 | 1454-84-8 |
| Hexadecanal | Hexadecanal is a free fatty aldehyde present in animals. | 240.42 | 629-80-1 |
| Heneicosane | Heneicosane is a pheromone that inhibits the production of aflatoxins. Heneicosane is an aroma component isolated from Streptomyces philanthi RL-1-178 or Serapias cordigera. | 296.57 | 629-94-7 |
| 1-Hydroxyoctadecane | Octadenol is a fatty alcohol present in human and is normally incorporated into plasmalogen lipids. Sjogren-Larsson syndrome is defined by the triad of ichthyosis, mental retardation, and spasticity, and patients accumulate fatty alcohols such as Octadenol in the plasma and cultured fibroblasts. | 270.49 | 112-92-5 |
| 2,5-dimethoxycyclohexa-2,5-diene-1,4-dio | 2,5-dimethoxycyclohexa-2,5-diene-1,4-dio is a natural product. The redox cycle of 2,5-dimethoxybenzoquinone is a source of reducing equivalent for the regeneration of Fe2+ and H2O2 in brown rot fungal decay of wood. | 168.15 | 3117-03-1 |
| Octadecane | Octadecane is a natural product. | 254.50 | 593-45-3 |
| Methyl behenate | Methyl behenate is a natural compound, is an ester form of docosanoic acid . | 354.60 | 929-77-1 |
| L-Aspartic Acid 4-Benzyl Ester | L-Aspartic Acid 4-Benzyl Ester is a chemical compound | 223.22 | 2177-63-1 |
| beta-Escin | beta-Escin is a natural mixture of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent. | 1131.30 | 11072-93-8 |
| Lumichrome | Lumichrome is a natural metabolite of riboflavin. Lumichrome produced by Rhizobium and other bacterial species induces major developmental changes in plants at nanomolar concentrations. Lumichrome can stimulate larval metamorphosis in ascidians and activate the LasR quorum sensing receptor of bacteria. Lumichrome competitively inhibits the uptake of riboflavin by riboflavin transporters from prokaryotes and eukaryotes. | 242.23 | 1086-80-2 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine | 1,2-dioleoyl-sn-glycero-3-phosphocholine is a phospholipid containing the unsaturated long-chain (18:1) oleic acid inserted at the sn-1 and sn-2 positions. | 786.10 | 4235-95-4 |
| cis-4-Hydroxy-L-proline | cis-4-Hydroxy-L-proline is a proline analog that inhibits collagen synthesis and has been used as an anticancer compound. It exerts antifibrotic effects and has additionally been shown to inhibit the proliferation of selected normal cell types as well as malignant cells. | 131.13 | 618-27-9 |
| Glycyl-L-tyrosine | Glycyl-L-tyrosine is a dipeptide containing glycine and L-tyrosine. It is an amino acid inhibitor from potatoes. | 238.24 | 658-79-7 |
| DL-Tryptophan | DL-tryptophan exists as a zwitterion during crystallization. DL-tryptophan is used as an optimal medium supplement for culturing yeast. | 204.23 | 54-12-6 |
| Iminodiacetic acid | Iminodiacetic acid (IDA) is a chelating agent that strongly binds transition metals. It can be used for the removal of toxic metal ions from water and also serves as a biomarker to potentially predict the severity of ARDS (acute respiratory distress syndrome). | 133.10 g/mol | 142-73-4 |
| Docosane | Docosane, a straight chain alkane, can be used to synthesize structural composites with thermal energy storage/release capability. | 310.60 | 629-97-0 |
| L-ALANYL-L-TYROSINE | L-ALANYL-L-TYROSINE(H-Ala-Tyr-OH) is a tyrosine derivative. | 252.27 | 3061-88-9 |
| Adenine sulfate | Adenine sulfate(Adenine hemisulfate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry. | 368.33 | 321-30-2 |
| Calcium gluconate monohydrate | Calcium gluconate (Calcarea gluconica, Calcium gluconate anhydrous, Calcium D-gluconate, Calciofon, Glucobiogen) is element or mineral necessary for normal nerve, muscle, and cardiac function. Calcium as the gluconate salt helps to maintain calcium balance and prevent bone loss when taken orally. | 448.39 | 66905-23-5 |
| D-Phenylalanine | D-Phenylalanine, a carboxypeptidase A, endorphinase and enkephalinase inhibitor, enhances endorphin production and diminishes pain. | 165.19 | 673-06-3 |
| Minocycline (CL 59806) HCl | Minocycline (CL 59806,Minocin) HCl is the most lipid soluble and most active tetracycline antibiotic, binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis. | 493.94 | 13614-98-7 |
| L-Abrine | L-Abrine (N-Methyl-L-tryptophan), an extremely toxic toxalbumin found in the seeds of the rosary pea, is a ribosome inhibiting protein. | 218.25 | 526-31-8 |
| Sodium Hyaluronate | Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan found in various connective tissue of humans. | 401.30 | 9067-32-7 |